Useful links

Websites which include classifications for BRCA1, BRCA2 and other cancer risk genes.

  • BRCA exchange website providing curated classification and other relevant information – Database
  • ClinVar public archive of reports of relationships between genetic variation and phenotypes – Database
    Search BRCA1 or BRCA2, and fiter Review Status (left-hand site) for Expert panel to see ENIGMA curated classifications.
  • The Breast Cancer Information Core (BIC) – Database
    Database of BRCA1 and BRCA2 mutations including VUS that have been voluntarily submitted by researchers, clinicians, counselors and nurses. Classifications results are shown when available.
  • BRCA multifactorial likelihood classification databases – Database
  • HCI Breast Cancer Genes Prior Probabilities- Database
  • A-GVGD database providing GVGD scores for missense variants – Database

Websites which include information on functional analysis of BRCA variants

  • BRCA1 CIRCOS – Website
  • LOVD BRCA1 Unique Variant View – Website
    Filter at top for all records describing functional studies
  • LOVD BRCA2 Unique Variant View – Website
    Filter at top for all records describing functional studies