Working Groups
All working groups are focused on research and translation related to BRCA1, BRCA2 and other known or suspected breast cancer genes
Analytical
Purpose/Scope of Working Group
To design and implement studies that improve, develop and apply statistical analyses for assessing clinical relevance of variants.
Splicing
Purpose/Scope of Working Group
To conduct large-scale studies that improve the clinical classification of likely spliceogenic variants.
Functional
Purpose/Scope of Working Group
To develop and use functional assays to contribute to the classification (interpretation) of variants.
Pathology
Purpose/Scope of Working Group
To identify tumor markers to be integrated into the multifactorial likelihood model for clinical interpretation of variants.
Clinical
Purpose/Scope of Working Group
To translate into the clinical arena relevant information regarding classification of variants of uncertain clinical significance.